IDENTIFICATION AND VALIDATION OF CORE GENES FOR TYPE 2 DIABETES MELLITUS BY INTEGRATED ANALYSIS OF SINGLE-CELL AND BULK RNA-SEQUENCING

Identification and validation of core genes for type 2 diabetes mellitus by integrated analysis of single-cell and bulk RNA-sequencing

Abstract Background The exact mechanisms of type 2 diabetes mellitus (T2DM) remain largely unknown.We intended to authenticate critical genes linked to T2DM progression by tandem single-cell sequencing and general transcriptome sequencing data.Methods T2DM single-cell RNA-sequencing data were submitted by the Gene Expression Omnibus (GEO) database

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Online communities as childcare resources among households with young children in metropolitan areas in Japan

This paper examines the relation between the the role of the use of the Internet, online communities, Bumper Accent Piece and households with young children.As parentiyoung networks have changed the Internet has been drawing attention as a source for providing childcare information and for networking with other parents.Since the 1990s, the deregula

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Prevalence and co-occurrence of compulsive buying, problematic Internet and mobile phone use in college students in Yantai, China: relevance of self-traits

Abstract Background Until now, most research in the prevalence of compulsive buying (CB) has been developed from samples in western developed countries, this study aimed to estimate the prevalence and co-morbidities of CB, problematic Internet use (PIU) and problematic mobile phone use (PMPU) in college students in Yantai, China.Moreover, based on

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Bodychecking rules and concussion in elite hockey.

Athletes participating in contact sports such as ice hockey are exposed to a high 5 Piece Full Panel Bedroom risk of suffering a concussion.We determined whether recent rule changes regulating contact to the head introduced in 2010-11 and 2011-12 have been effective in reducing the incidence of concussion in the National Hockey League (NHL).A leagu

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Case Report: A Sudden Thyroid-Related Death of a 15-Year-Old Girl

A 15-year-old young girl was found dead at home.There were no indications of any intervention or the application of force.On the previous day, she was admitted to hospital because of palpitations, fatigue, a headache, and a swollen neck.During a physical examination, a swollen thyroid gland and tachycardia were found.In the family history, her moth

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